Publications

Peer-reviewed Publications

Common pitfalls of stem cell differentiation: a guide to improving protocols for neurodegenerative disease models and research.
Engel, M., Do-Ha, D., Sanz-Muñoz, S., Ooi, L., 2016.
Cellular and Molecular Life Sciences. doi: 10.1007/s00018-016-2265-3
Details – PublisherPubMED

mGluR2/3 agonist LY379268 rescues NMDA and GABAA receptor level deficits induced in a two-hit mouse model of schizophrenia.
Engel, M., Snikeris, P., Matosin N, Newell, K.A., Huang, X.-F., Frank, E., 2016.
Psychopharmacology (Berl.). doi: 10.1007/s00213-016-4230-0 & Erratum
Details – Publisher – Pubmed

Metabotropic glutamate receptor 5 and its trafficking molecules, Norbin and Tamalin, are increased in the CA1 hippocampal region of subjects with schizophrenia.
Matosin N, Fernandez-Enright F, Lum JS, Andrews JL, Engel M, Huang XF, Newell KA. 
Schizophrenia Research. 2015. 166(1-3): 212-218. doi: 10.1016/j.schres.2015.05.001
Publisher – Pubmed

Growth-factor dependent expression of the translationally controlled tumour protein TCTP is regulated through the PI3-K/Akt/mTORC1 signalling pathway.
Bommer UA, Iadevaia V, Chen J, Knoch B, Engel M, Proud CG.
Cell Signal. 2015 Apr 30. pii: S0898-6568(15)00145-X. doi: 10.1016/j.cellsig.2015.04.011. [Epub ahead of print]
Publisher Pubmed

Alterations of mGluR5 and its endogenous regulators Norbin, Tamalin and Preso1 in schizophrenia: towards a model of mGluR5 dysregulation.
Matosin N, Fernandez-Enright F, Fung SJ, Lum JS, Engel M, Andrews JL, Huang XF, Weickert CS, Newell KA. 
Acta Neuropathol. 2015 Mar 17. [Epub ahead of print]
Details Publisher Pubmed

Neuregulin 1 prevents phencyclidine-induced behavioral impairments and disruptions to GABAergic signaling in mice.
Engel M, Snikeris P, Jenner A, Karl T, Huang X, Frank E.
Int J Neuropsychopharmacol. 2014 Dec 25. pii: pyu114. doi: 10.1093/ijnp/pyu114. [Epub ahead of print]
DetailsPublisherPubmed

Negativity towards negative results: a discussion of the disconnect between scientific worth and scientific culture.
Matosin N, Frank E, Engel M, Lum JS, Newell KA.
Dis Model Mech. 2014 Feb;7(2):171-3. doi: 10.1242/dmm.015123.
DetailsPublisherPubmed

Neuregulin-1 signalling and antipsychotic treatment: potential therapeutic targets in a schizophrenia candidate signalling pathway.
Deng C, Pan B, Engel M, Huang XF.
Psychopharmacology (Berl). 2013 Mar;226(2):201-15. doi: 10.1007/s00213-013-3003-2. Epub 2013 Feb 7. Review.
DetailsPublisherPubmed

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Editorials and Articles

Positives in negative results: when finding ‘nothing’ means something. The Conversation, 25. September 2014.

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